A Randomized Controlled Trial Comparing Contrast Baths to Cryotherapy in Patients with a Wrist Fracture

Cryotherapy and contrast baths are common modalities used to treat edema. Despite the fact that many hand therapists report using contrast baths with their patients, there is still little evidence on the effectiveness of them. A Randomized Controlled Trial-Repeated Measures Design was employed to compare the effectiveness of contrast baths to cryotherapy. Participants were recruited after a period of post-fracture immobilization. Blind assessors attained measurements in range of motion, pain, and edema in the 1st, 2nd, and 4th weeks. Participants were randomly assigned to either use cryotherapy or contrast baths at home during the 4-week study period. The participants in this study were asked to keep a home program log to record the number of times that they were able to complete their assigned modality. Also, at the final measurement appointment, the participants were asked to complete a survey indicating their satisfaction with their assigned home program. The results from the ANOVA indicated that there was statistical significance for all the measurements (p \u3c .05) except for palm circumferential and volumeter. The results from the home program logs indicated that the adherence for contrast baths had a mean of 2.03 (SD = 0.76) times per day and the cryotherapy group had a mean of 1.75 (SD = 0.98) times per day. The researchers also noted a trend that the contrast baths group may have a larger effect in the first two weeks of treatment, while the cryotherapy group may have more gradual improvements throughout the four weeks. The results of this study found that adherence for contrast baths and cryotherapy had similar home program adherence and that the participants had similar experiences

Transitioning from acute to primary health care nursing: an integrative review of the literature

Aims and objectives This paper seeks to explore the transition experiences of acute care nurses entering employment in primary health care settings. Background Internationally the provision of care in primary health care settings is increasing. Nurses are moving from acute care settings to meet the growing demand for a primary health care workforce. While there is significant research relating to new graduate transition experiences, little is known about the transition experience from acute care into primary health care employment. Design An integrative review, guided by Whittemore and Knafl\u27s (2005) approach, was undertaken. Following a systematic literature search eight studies met the inclusion criteria. Methods Papers which met the study criteria were identified and assessed against the inclusion and exclusion criteria. Papers were then subjected to methodological quality appraisal. Thematic analysis was undertaken to identify key themes within the data. Results Eight papers met the selection criteria. All described nurses transitioning to either community or home nursing settings. Three themes were identified: (1) a conceptual understanding of transition, (2) role losses and gains and (3) barriers and enablers. Conclusion There is a lack of research specifically exploring the transitioning of acute care nurses to primary health care settings. To better understand this process, and to support the growth of the primary health care workforce there is an urgent need for further well-designed research. Relevance to clinical practice There is an increasing demand for the employment of nurses in primary health care settings. To recruit experienced nurses it is logical that many nurses will transition into primary health care from employment in the acute sector. To optimise retention and enhance the transition experience of these nurses it is important to understand the transition experience

Special Libraries, December 1940

Volume 31, Issue 10https://scholarworks.sjsu.edu/sla_sl_1940/1009/thumbnail.jp

For younger patients with stroke, does rehabilitation in the home, compared to rehabilitation in the day clinic, improve early level of activity participation?

The main purpose of this study was to determine if 3 weeks of rehabilitation in the home setting improves activity to a larger extent and facilitates rehabilitation in younger patients following a stroke compared to patients receiving intervention in an outpatient rehabilitation clinic. Cost effectiveness among these interventions was also described

Localization and Functional Characterization of the Alternative Oxidase in Naegleria

The Alternative oxidase (AOX) is a protein involved in maintaining the Krebs cycle in instances where the respiratory chain has been inhibited, while allowing for the maintenance of cell growth and necessary metabolic processes for survival. Among eukaryotes, alternative oxidases have disperse distribution and are found in plants, fungi and a few protists, including Naegleria ssp. Naegleria species are free-living unicellular amoeboflagellates, and include the pathogenic species of N. fowleri, the so-called brain eating amoeba. Using a multidisciplinary approach, we aimed to understand the evolution, localization and function of AOX and the role that plays in Naegleria’s biology. Our analyses suggest that the protein was present in last common ancestor of the genus and structure prediction showed that all functional residues are also present in Naegleria species. Using a combination of cellular and biochemical techniques, we also functionally characterize N. gruberi’s AOX in its mitochondria and we demonstrate that its inactivation affects its proliferation. Consequently, we discuss the benefits of the presence of this protein in Naegleria species, along with its potential pathogenicity role in N. fowleri. We predict that our findings will spearhead new explorations to understand the cell biology, metabolism and evolution of Naegleria and other free-living relatives

Distinct phenotype of neutrophil, monocyte, and eosinophil populations indicates altered myelopoiesis in a subset of patients with multiple myeloma

Hematologic malignancies, including multiple myeloma (MM), promote systemic immune dysregulation resulting in an alteration and increased plasticity of myeloid cell subsets. To determine the heterogeneity of the myeloid cell compartment in the peripheral blood of patients with MM, we performed a detailed investigation of the phenotype and function of myeloid subpopulations. We report that a subset of MM patients exhibits a specific myeloid cell phenotype indicative of altered myelopoiesis characterized by significant changes in the properties of circulating granulocytic, monocytic, and eosinophilic populations. The subset, referred to as MM2, is defined by a markedly elevated level of CD64 (FcγRI) on the surface of circulating neutrophils. Compared to healthy controls or MM1 patients displaying intermediate levels of CD64, neutrophils from MM2 patients exhibit a less differentiated phenotype, low levels of CD10 and CXC chemokine receptor 2 (CXCR2), increased capacity for the production of mitochondrial reactive oxygen species, and an expansion of CD16neg immature neutrophil subset. Classical and patrolling monocytes from MM2 patients express elevated levels of CD64 and activation markers. MM2 eosinophils display lower levels of C-C Chemokine receptor 3 (CCR3), Toll-like receptor 4 (TLR4, CD284), and tissue factor (TF, CD142). The MM2 (CD64high) phenotype is independent of age, race, sex, and treatment type. Characteristic features of the MM2 (CD64high) phenotype are associated with myeloma-defining events including elevated involved/uninvolved immunoglobulin free light chain (FLC) ratio at diagnosis. Detailed characterization of the altered myeloid phenotype in multiple myeloma will likely facilitate the identification of patients with an increased risk of disease progression and open new avenues for the rational design of novel therapeutic approaches

Intertidal No. 1

For the first year ever, Intertidal has surfaced to showcase the art of Cal Poly\u27s students and faculty. An \u27intertidal zone\u27 is an area where the ocean meets the land--hidden during the high tide and exposed during the low. Our journal embodies the moment where the tide recedes, revealing stories previously hidden

Digitization workflows for flat sheets and packets of plants, algae, and fungi

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141708/1/aps31500065.pd